Featuring Michael J. Joyner, M.D.
Frank & Shari Caywood Professor
Department of Anesthesiology & Perioperative Medicine
In this talk Dr. Joyner will critique the widely pitched “genomics is transforming medicine” narrative. To do this, he will review the false promise that the Human Genome Project would lead to a “genetic revolution in medicine” – now called Precision Medicine. Dr. Joyner will document how this narrative has underperformed, explain why it has underperformed and show that a “genomic bubble” has now emerged and been amplified by buzzwords like big data, machine learning and artificial intelligence. This discussion will serve as a template to highlight key biological principles that are overlooked when too much focus is aimed at genes. The twin problems of hype and the limits of big science will also be reviewed. He will close by asking “what problem” are we trying to solve, and suggest some approaches that are likely to be far more effective than those stemming from the gene centric world view that now dominates the biomedical landscape.
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